Dynamic self-organisation of haematopoiesis and (a)symmetric cell division
نویسندگان
چکیده
منابع مشابه
Inductive asymmetric cell division
C. elegans, with its invariant cell lineage, provides a powerful model system in which to study signaling-dependent asymmetric cell division. The C. elegans β-catenin-related protein, WRM-1, specifies endoderm at the 4-cell stage during the first cell signaling-induced asymmetric cell division of embryogenesis. During this interaction, Wnt signaling and the cell cycle regulator CDK-1 act togeth...
متن کاملG Protein Signaling and Asymmetric Cell Division
Asymmetric cell division depends on the polarization of the dividing cell for the correct alignment of the mitotic spindle and the localization of cytoplasmic determinants. Receptor-independent activation of heterotrimeric G proteins by the Drosophila GoLoco protein Partner of Inscuteable seems to represent a novel mechanism to control these events.
متن کاملMechanisms of Asymmetric Stem Cell Division
Stem cells self-renew but also give rise to daughter cells that are committed to lineage-specific differentiation. To achieve this remarkable task, they can undergo an intrinsically asymmetric cell division whereby they segregate cell fate determinants into only one of the two daughter cells. Alternatively, they can orient their division plane so that only one of the two daughter cells maintain...
متن کاملControl of Apoptosis by Asymmetric Cell Division
Asymmetric cell division and apoptosis (programmed cell death) are two fundamental processes that are important for the development and function of multicellular organisms. We have found that the processes of asymmetric cell division and apoptosis can be functionally linked. Specifically, we show that asymmetric cell division in the nematode Caenorhabditis elegans is mediated by a pathway invol...
متن کاملIntegrating self-organisation into dynamic coalition formation
In some real systems, e.g., sensor networks, individual agents will often need to form coalitions to accomplish complex tasks. Due to communication or computation constrains, it is infeasible for agents to directly interact with all other peers to form coalitions. Most current coalition formation works, however, overlooked this aspect. Those works usually did not provide an explicitly modeled a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Theoretical Biology
سال: 2017
ISSN: 0022-5193
DOI: 10.1016/j.jtbi.2016.11.030